Postdoctoral Fellow Ocular Immunology Scientist
- Employer
- Spark Therapeutics
- Location
- Philadelphia, Pennsylvania. Hybrid and remote options available for select opportunities.
- Salary
- Salary not provided
- Closing date
- May 16, 2023
View more
- Discipline
- Life Sciences, Immunology, Health Sciences, Drug Development
- Job Type
- Postdoc Fellowship, Staff Scientist
- Organization Type
- Pharma
Job Details
As a member of the Immunology Team in the Research and Technology Department, the Ocular Immunology Scientist characterizes the immune response to AAV-based gene transfer in the eye. S/he designs and executes studies using immuno-competent in vitro and in vivo models to identify mechanisms of anti-vector or anti-transgene immune response. S/he uses the generated data to identify and validate novel immunosuppressive regimens enhancing positive outcomes of gene therapy. S/he partners with internal ocular gene transfer experts and has an access to the cutting-edge technologies for sample analysis. S/he optimizes new imaging techniques enabling phenotyping on the immune response in the eye.
Responsibilities
Describe the essential daily job functions and include % of time spent on each.% of Time
Job Function and Description
50
Designs and execute studies using ocular gene transfer immuno-competent in vitro and in vivo models
20
Optimization of the high content imaging platform for the ocular tissues
15
Analyze and present data at internal and external meetings
15
Keep abreast of new scientific/technology development by participating in scientific meetings/seminars and through regular scientific review.
Requirements
- Ph.D. in Ocular Immunology or related field
- A publication track record
- A background in ocular immunology
Please be aware that Spark mandates COVID-19 vaccination of all employees regardless of work location. Accommodations may be made in accordance with applicable law.
Spark Therapeutics does not accept unsolicited resumes/candidate profiles from any source other than directly from candidates. Any unsolicited resume/candidate profile submitted through our website or to personal email accounts of employees of Spark Therapeutics are considered property of Spark Therapeutics and are not subject to payment of agency fees.
Nearest Major Market: Philadelphia
Join the Spark Team
We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable - until now.
We don't follow footsteps. We create the path.
Learn more about Spark Therapeutics and view other openings.
Company
At Spark Therapeutics, a fully integrated, commercial company committed to discovering, developing and delivering gene therapies, we challenge the inevitability of genetic diseases, including blindness, hemophilia, lysosomal storage disorders and neurodegenerative diseases.
Founded in March 2013 as a result of the technology and know-how accumulated over two decades at Children’s Hospital of Philadelphia (CHOP), our investigational therapies have the potential to provide long-lasting effects, dramatically and positively changing the lives of patients with conditions where no, or only palliative, therapies exist. Greater understanding of the human genome and genetic abnormalities have allowed our scientists to tailor investigational therapies to patients suffering from very specific genetic diseases. This approach holds great promise in developing effective treatments to a host of inherited diseases. Our initial focus is on treating orphan diseases.
Headquartered in dynamic Philadelphia, we are a diverse, experienced team united in our goal to break down barriers for people and families affected by genetic diseases. As our name suggests, our investigational, one-time therapies are designed to spark healthy biology, and deliver potentially life-altering transformation for people and families affected by genetic disease. Spark is a member of the Roche Group.
- Website
- http://sparktx.com/
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