Postdoctoral Fellow in Cancer Biology

At Moffitt Cancer Center, we strive to be the leader in understanding the complexity of cancer and applying these insights to contribute to the prevention and cure of cancer. Our diverse team of over 9,000 are dedicated to serving our patients and creating a workspace where every individual is recognized and appreciated. For this reason, Moffitt has been recognized on the 2023 Forbes list of America’s Best Large Employers and America’s Best Employers for Women, Computerworld magazine’s list of 100 Best Places to Work in Information Technology, DiversityInc Top Hospitals & Health Systems and continually named one of the Tampa Bay Time’s Top Workplace. Additionally, Moffitt is proud to have earned the prestigious Magnet® designation in recognition of its nursing excellence. Moffitt is a National Cancer Institute-designated Comprehensive Cancer Center based in Florida, and the leading cancer hospital in both Florida and the Southeast. We are a top 10 nationally ranked cancer center by Newsweek and have been nationally ranked by U.S. News & World Report since 1999.
Working at Moffitt is both a career and a mission: to contribute to the prevention and cure of cancer. Join our committed team and help shape the future we envision.

Summary

Postdoctoral Fellow in Cancer Biology

Dr. Lixin Wan's laboratory at Moffitt Cancer Center Department of Molecular Oncology is dedicated to understanding how protein post-translational modifications (ubiquitination, phosphorylation, etc.) shape the proteomic network and how tumor cells rewiring signaling and metabolic pathways to gain proliferative advantage as well as to escape immune surveillance. We are currently searching for novel functions of the ubiquitin pathway in tumor cell transcriptome reprogramming, metabolism, dormancy, and immune evasion (Qing et al, Nature Communications 2019; Han et al. Nature Communications 2019). The lab uses multidisciplinary approaches to address a dynamic range of scientific questions in cancer biology and beyond. Postdoctoral fellows in the lab are encouraged to receive career development training for future independent research positions.

The Ideal Candidate:

• Experienced in basic molecular biology, cell biology and biochemistry techniques including cloning, virus delivery system, CRISPR/Cas9 system, DNA/RNA manipulation, protein purification, and immunoblot.
• Animal handling, mouse modeling and small animal imaging experience.
• Basic imaging techniques including immunofluorescence, live color imaging.
• Basic bioinformatics skills.
• Previous experience in next-generation sequencing techniques (RNA-seq, ChIP-seq, etc) and/or proteomics is a plus.
• Previous immunology experience is a plus.

Responsibilities:

• Work with PI on the project planning; design and conduct experiments independently; document and organize the data routinely.
• Learn and develop research techniques and lab protocols.
• Develop scientific writing and presentation skills.
• Work with collaborators and core facility staff on interdisciplinary experiments.
• Supervise research assistants and graduate students.

Credentials and Qualifications:

• MD or PhD in Cancer Biology, Molecular and Cellular Biology, Genetics or related is required.

Interested applicants should send a single PDF file that includes a cover letter summarizing their research training and accomplishments, a personal statement of scientific interests and goals, current CV with recent publications, and contact information for three references to Dr. Lixin Wan (Lixin.Wan@moffitt.org).